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I think maybe his point was that in "equivalent doses", there is not much difference in these, except maybe for cost and duration of action.

The non-sedating alternative is Buspar (buspirone), which has never achieved the popularity of the benzodiazepines.

Individual patient response to medications can vary; therefore, the clinician can potentially overshoot the desired level of anesthesia.

Clinicians must be prepared for this and should have emergency apparatus available in case problems arise.

Benzodiazepine Uses: Benzodiazepines are a large drug class (see Table 1) and have a long history of development, starting with the first FDA-approvals in the 1960s, chloridiazepoxide (Librium) and diazepam (Valium).Benzodiazepines are a class of medications that work in the central nervous system and are used for a variety of medical conditions.As a class, benzodiazepines are similar in how they work in the brain but have different potencies, durations of actions, and receptor site affinities. What I think this gentleman wanted to know, is assuming an equal dose according to some standard "benzodiazapine equivalency chart" which BZ is least sedating at it's standardized dosage.So, for example, of 0.5 mg Xanax, or 20 mg or Serax, or 1 mg Ativan, or 25 mg Libruim, which is least sedating.Maybe some folks didn't like Buspar because it cost a vast fortune (as opposed to dirt cheap generic benzos) and for many didn't work.